Quiz - Aldehydes and Ketones | Aldehydes and Ketones – Part 2

1

What is the product of a Wolff-Kishner reduction?

An alkane

An alcohol

An enamine

An amine

Wolff-Kishner reduction:

2

Which of the following statements is correct about addition reactions of hydrogen cyanide to carbonyls?

The carbonyl oxygen is protonated by HCl

The carbonyl oxygen is protonated by HCN

The alkoxide intermediate is protonated by HCN

There is no proton transfer step in the mechanism of this reaction

Addition of HCN:

3

What is the product of a Wittig reaction?

A phosphorus ylide

An alkene

An alkyne

An aldehyde

Wittig reaction:
 

4

Which of the following statements is correct about Wittig reaction?

A cyclic intermediate called oxaphosphetane is formed

An enol forms and reacts with phosphorus ylide

Phosphonium ylides are electrophilic

NaOH can be used to generate phosphorus ylides

Wittig reaction:

5

What is the product of a Baeyer-Villiger oxidation?

An ester and a peroxycarboxylic acid

A ketone and a peroxycarboxylic acid

A ketone and a carboxylic acid

An ester and a carboxylic acid

Baeyer-Villiger Oxidation:
 

6

Which of the following alkyl substituents migrates the fastest in a Baeyer-Villiger reaction?

Primary alkyl

Secondary alkyl

Tertiary alkyl

Quaternary alkyl

With asymmetric ketones, esters can be selectively formed by migration of only one of the substituents. Migratory aptitudes in the Baeyer-Villiger reaction: Methyl  <  Primary Alkyl < Phenyl ~ Secondary Alkyl < Tertiary Alkyl