Organic Chemistry 1
Introduction to Organic Chemistry: bonding theory, chemical and physical properties, structure and reactivities, isomerism, stereochemistry. Introduction to substitution, addition, and elimination reactions. Methodology for retrosynthetic analysis.
The structure and bonding in organic molecules are studied in this chapter: atomic structure and electron configurations, ionic and covalent bonds (octet rule), formal charges, hybridization types, resonance forms, Lewis structure and other molecular structures
Structure and reactivity in organic chemistry are studied in this chapter: Bronsted acids/bases and acid strength, Lewis acids/bases, nucleophiles and electrophiles, chemical functional groups, types of isomers, types of arrow, heterolytic and homolytic cleavage
Reactions of alkanes are studied in this chapter: IUPAC nomenclature, name and properties of alkanes, chemical equivalence, primary, secondary, tertiary, quaternary in chemistry, radicals and their stability, radical chain reactions, halogenation of alkanes (mechanism, products and selectivity)
Cycloalkanes are studied in this chapter: nomenclature of cycloalkanes, types of strain, conformers, chair conformations (strain free conformations of cyclohexane), substituted cyclohexanes
Stereoisomerism concept is studied in this chapter: chirality of chemical compounds, absolute configuration of a stereocenter, types of stereoisomers (enantiomers, diastereomers, meso compound), optical activity of stereoisomers, racemic mixture and enantiomeric excess
Properties of alkyl halides and nucleophilic substitutions are studied in this chapter: physical properties and naming of alkyl halides, polar reactions, nucleophilic substitution reactions, in-depth study of SN reactions, competition between SN1 and SN2
Further reactions of alkyl halides are studied in this chapter: elimination reactions (E reactions), competition between E1 and E2, competition between SN and E reactions
The properties and sunthesis of alcohols, ethers, and epoxides are studied in this chapter: properties and naming of alcohols, synthesis of alcohols (SN reaction, reduction of carbonyls, organometallics), Williamson ether synthesis, intramolecular Williamson epoxide synthesis
The reactivity of alcohols, ethers and epoxides are studied in this chapter: typical reactions of alcohols (deprotonation, substitution, elimination, oxidation), preparation of alkoxides, nucleophilic substitutions of alcohols, dehydration of alcohols, carbocation rearrangements, reactivity of ethers, epoxide opening
The strategies in retrosynthesis are studied in this chapter: protection / deprotection of chemical functional groups, retrosynthetic analysis, summary of the chemical transformations seen so far
Midterm 1 includes 7 questions and it covers Chapters 1, 2 and 3 of Organic Chemistry 1. At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 1.
Midterm 2 includes 8 questions and it covers chapters 1 to 6 of Organic Chemistry 1 (mainly chapters 4, 5 and 6). At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 2.
Final Exam includes 14 questions and it covers all chapters of Organic Chemistry 1. At the end of the test you can see the answers and determine whether you have solved the questions. You have 3 hours to resolve Final Exam.