Organic Chemistry 1

Organic Chemistry 1 - Chemistry Coach

Introduction to Organic Chemistry: bonding theory, chemical and physical properties, structure and reactivities, isomerism, stereochemistry. Introduction to substitution, addition, and elimination reactions. Methodology for retrosynthetic analysis.
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Concepts
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Exercises
Exams
The structure and bonding in organic molecules are studied in this chapter: atomic structure and electron configurations, ionic and covalent bonds (octet rule), formal charges, hybridization types, resonance forms, Lewis structure and other molecular structures
Atomic Structure Electron Configuration Ionic and Covalent Bonds Formal Charge Hybridization and Geometry Resonance Forms Shorthand Representations Lewis Structures
Structure and reactivity in organic chemistry are studied in this chapter: Bronsted acids/bases, acid strength, Lewis acids/bases, nucleophiles and electrophiles, chemical functional groups, types of isomers, types of arrows, heterolytic and homolytic cleavage
Bronsted Acids / Bases Lewis Acids / Bases Nucleophile vs. Electrophile Functional Groups Types of Isomers Heterolytic vs. Homolytic Cleavage Acid Strength Types of Arrows
Reactions of alkanes are studied in this chapter: IUPAC nomenclature, name and properties of alkanes, chemical equivalence, primary, secondary, tertiary, quaternary structures in chemistry, radicals and their stability, radical chain reactions, halogenation of alkanes (mechanism, products and selectivity)
IUPAC Nomenclature Chemical Equivalence Primary, Secondary, Tertiary, Quaternary in Chemistry Radicals Halogenation of Alkanes Selectivity of Halogenation Properties of Alkanes Nomenclature of Alkanes
Cycloalkanes are studied in this chapter: nomenclature of cycloalkanes, types of strain, conformers, chair conformations (strain free conformations of cyclohexane), substituted cyclohexanes
Nomenclature of Cycloalkanes Conformers Cycloalkane Strains Conformations of Cyclohexane Substituted Cyclohexanes
Stereoisomerism concept is studied in this chapter: chirality of chemical compounds, absolute configuration of a stereocenter, types of stereoisomers (enantiomers, diastereomers, meso compound), optical activity of stereoisomers, racemic mixture and enantiomeric excess
Chirality Absolute Configuration R / S Enantiomers vs. Diastereomers Optical Activity Meso Compounds Racemic Mixture and Enantiomeric Excess
Properties of alkyl halides and nucleophilic substitutions are studied in this chapter: physical properties and naming of alkyl halides, polar reactions, nucleophilic substitution reactions, in-depth study of SN reactions, competition between SN1 and SN2
Properties of Alkyl Halides Polar Reactions Nucleophilic Substitution Reactions SN2 Reactions SN1 Reactions Summary SN1 vs. SN2 Reactions Nomenclature of Alkyl Halides Factors Favoring SN1 or SN2
Further reactions of alkyl halides are studied in this chapter: elimination reactions (E reactions), competition between E1 and E2, competition between SN and E reactions
Alkyl Halide Reactions E2 Reactions E1 Reactions Summary E1 vs. E2 Reactions Competition Between SN1, SN2, E1, E2 Factors Favoring E1 or E2 Zaitsev Product
The alcohols, ethers, and epoxides are studied in this chapter: properties and naming of alcohols, synthesis of alcohols (SN reaction, reduction of carbonyls, organometallics), Williamson ether synthesis, intramolecular Williamson epoxide synthesis
Properties of Alcohols Nomenclature of Alcohols Preparation of Alcohols by SN Reactions Synthesis of Alcohols by Reduction of Carbonyls Synthesis of Alcohols with Organometallics Synthesis of Ethers Synthesis of Epoxides
The reactivity of alcohols, ethers and epoxides are studied in this chapter: typical reactions of alcohols (deprotonation, substitution, elimination, oxidation), preparation of alkoxides, nucleophilic substitutions of alcohols, dehydration of alcohols, carbocation rearrangements, reactivity of ethers, epoxide opening
Typical Reactions of Alcohols Preparation of Alkoxides Nucleophilic Substitutions of Alcohols Dehydration of Alcohols Carbocation Rearrangements Reactivity of Ethers Reactivity of Epoxides
Retrosynthetic strategies are studied in this chapter: protecting groups, protection and deprotection, alcohol protecting groups, carbonyl protecting groups, retrosynthetic analysis, retrosynthetic strategies
Protection - Deprotection Alcohol Protecting Groups Carbonyl Protecting Groups Retrosynthetic Analysis Retrosynthesis Strategies
Midterm 1 includes 7 questions and it covers Chapters 1, 2 and 3 of Organic Chemistry 1. At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 1.
Questions
60 Minutes
Midterm 2 includes 8 questions and it covers chapters 1 to 6 of Organic Chemistry 1 (mainly chapters 4, 5 and 6). At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 2.
Questions
60 Minutes
Final Exam includes 14 questions and it covers all chapters of Organic Chemistry 1. At the end of the test you can see the answers and determine whether you have solved the questions. You have 3 hours to resolve Final Exam.
Questions
180 Minutes