Organic Chemistry 2
Continuation of Organic Chemistry I. Methods of analysis, chemistry of hydrocarbons (alkenes, alkynes, aromatic hydrocarbons), chemistry of the carbonyl group (aldehydes, ketones, carboxylic acids, carboxylic acid derivatives). Emphasis on mechanistic aspects of reactions and effects of molecular structure on reactivity.
Alkenes are studied in this chapter: name and properties of alkenes, pi bond in chemistry, geometric isomers E and Z, preparation of alkenes by elimination reactions or alcohol dehydration, Saytzev and Hofmann rules, degree of unsaturation of a chemical compound
The reactions of alkenes are studied in this chapter: hydrogenation, electrophilic addition of hydrogen halides, electrophilic hydration, electrophilic halogenation, hydroboration-oxidation, epoxide synthesis, vicinal syn dihydroxylation, ozonolysis, radical bromination
Alkynes are studied in this chapter: name and properties of alkynes, preparation of alkynes, reduction reactions, electrophilic addition reactions, anti-Markovnikov additions
The delocalized π systems are studied in this chapter: overlap of 3 adjacent p orbitals, allylic reactions, conjugated dienes and their reactions, Diels-Alder cycloadditions, kinetic and thermodynamic control
Benzene derivatives and aromaticity are studied in this chapter: name and properties of benzene derivatives, Hückel’s rule - aromatic, antiaromatic, non-aromatic systems, electrophilic aromatic substitution, halogenation of benzene
The electrophilic attacks of benzene derivatives are studied in this chapter: electrophilic substitution of substituted benzenes, activating and deactivating substituents, meta- ortho- para- directing substituents, synthesis strategies
Aldehydes and ketones are studied in this chapter: name, properties and synthesis of carbonyls, addition reactions: addition of hydride and organometallic reagents, addition of water, addition of alcohols, addition of ammonia and its derivatives
Enols, enolates and aldol condensation are studied in this chapter: acidity of carbonyls, keto-enol equilibria, alkylation of carbonyls, aldol and cross-aldol condensation, unsaturated aldehydes and ketones (1,2- and 1,4-additions)
Carboxylic acids are studied in this chapter: name, properties and synthesis of carboxylic acids, reduction and addition-elimination reactions, preparation of carboxylic acid derivatives: acyl halides, carboxylic anhydrides, esters, amides
Carboxylic acid derivatives are studied in this chapter: properties and relative reactivity of carboxylic acid derivatives, chemistry of acyl halides, chemistry of esters, chemistry of carboxylic anhydrides, chemistry of amides
Midterm 1 includes 7 questions and it covers Organic Chemistry 1 and Chapters 1, 2 and 3 of Organic Chemistry 2. At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 1.
Midterm 2 includes 6 questions. It covers Organic Chemistry 1 and chapters 1 to 6 of Organic Chemistry 2 (mainly chapters 4, 5 and 6). At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 2.
Final Exam includes 12 questions and it covers all chapters of Organic Chemistry 1 and 2. At the end of the test you can see the answers and determine whether you have solved the questions. You have 2 hours to resolve Final Exam.