Carboxylic Acid Derivatives – Part 2 | Organic Chemistry 3
Step 1: Amidate formation
Step 2: Halogenation
Step 3: N-Haloamidate formation
Step 4: Rearrangement with halide elimination
Step 5: Hydration to the carbamic acid and decomposition
Alkanenitriles: Naming and Properties
The ending -ic acid of the carboxylic acid is replaced with -nitrile.
The substituent CN is called cyano.
The cyanocycloalkanes are called cycloalkanecarbonitriles.
Nitrile takes precedence over aldehyde, ketone, amine, alkene, alkyne.
- sp hybridization (linear geometry)
- IR: stretching vibration ~ 2250 cm-1
- NMR: 13C δ ~ 120 ppm
Hydrolysis of Nitriles
Nitriles and Organometallic reagents
Reduction of Nitriles