Organic Chemistry 3

Organic Chemistry 3 - Chemistry Coach

In-depth study of the aromatic hydrocarbons (benzene substituents) and the carbonyl group, chemistry of amines and their derivatives, chemistry of the heterocycles. Organic chemistry of biologically important molecules: carboxylic acids, carbohydrates, amino acids, peptides, proteins, natural products
Chapters
Concepts
Quizzes
Exercises
Exams
Additional reactions of carboxylic acid derivatives are studied in this chapter: chemistry of acid anhydrides: preparation and reactions, chemistry of amides: preparation, hydrolysis and reactions, nomenclature and properties of nitriles, chemistry of nitriles: preparation, hydrolysis and reactions.
The chemistry of the alpha carbon of a carbonyl is studied in this chapter: the alpha position, enols and tautomerization, the preparation of enolates and their reactivity, alpha halogenation, the haloform reaction, the alkylation of enolates, the malonic ester synthesis and acetoacetic ester synthesis.
Carbonyl condensation reactions are studied in this chapter: aldol and retro-aldol additions, aldol condensation, crossed aldol and intramolecular aldol reactions, Claisen condensation, Dieckmann cyclization, Michael reaction, Michael acceptors and donors, Stork enamine synthesis, Enamine Alkylation, Robinson annulation.
The benzylic and aromatic reactions of substituted benzene are studied in this chapter: reactivity of the benzylic position, benzylic oxidation and reduction, reduction of nitrobenzene, nucleophilic aromatic substitutions, elimination-addition via benzyne, reactivity of phenol, preparation and reactivity of diazonium salts.
Amines are studied in this chapter: nomenclature and properties of amines, preparation of amine by substitution reactions, reductive amination, and reductions, reactivity of amines, Hofmann elimination, reactions of amines with nitrous acid, Mannich reaction.
Heterocycles are studied in this chapter: reactivity of non-aromatic heterocycles, synthesis, properties and reactivity of aromatic heterocyclopentadienes, synthesis, properties and reactivity of pyridine
Carbon-carbon bond formation is studied in this chapter: coupling reactions with organocuprate reagents, Suzuki reaction, Heck reaction, Sonogashira reaction, properties and preparation of carbenes, carbene reactivities, Simmons-Smith reaction, metathesis reaction.
Carbohydrates are studied in this chapter: properties of carbohydrates, Fischer projection, naming and classification of carbohydrates, configuration of aldoses and ketoses, cyclic structures of sugars, Haworth projection, ester, ether, and N-glycoside formation, epimerization, oxidation and reduction of sugars, chain lengthening and shortening, polysaccharides.
Amino acids, peptides, and proteins are studied in this chapter: structure and properties of amino acids, synthesis of amino acids (Hell-Volhard-Zelinsky reaction, amidomalonate synthesis, Strecker synthesis, enantiopure synthesis), structure and properties of peptides, peptide sequencing by Edman degradation and enzymatic cleavage, synthesis of peptides, Merrifield solid-phase peptide synthesis, structures and functions of proteins.
Lipids are studied in this chapter: classes of lipids, waxes, triglycerides, reactions of triglycerides and fatty acids, phospholipids, phosphoglycerides, steroid structure, cholesterol and other major steroids, biosynthesis of cholesterol, eicosanoids, prostaglandins, terpenes, classification and biosynthesis of terpenes.
Midterm 1 includes 5 questions and it covers Organic Chemistry 1, Organic Chemistry 2 and Chapters 1, 2 and 3 of Organic Chemistry 3. At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 1.
Midterm 2 includes 5 questions and it covers Organic Chemistry 1, Organic Chemistry 2 and chapters 1 to 6 of Organic Chemistry 3 (mainly chapters 4, 5 and 6). At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 2.
Final Exam includes 13 questions and it covers all chapters of Organic Chemistry 1, 2 and 3. At the end of the test you can see the answers and determine whether you have solved the questions. You have 3 hours to resolve Final Exam.