Organic Chemistry 3

Organic Chemistry 3 - Chemistry Coach

In-depth study of the aromatic hydrocarbons (benzene substituents) and the carbonyl group, chemistry of amines and their derivatives, chemistry of the heterocycles. Organic chemistry of biologically important molecules: carboxylic acids, carbohydrates, amino acids, peptides, proteins, natural products
Chapters
Concepts
Quizzes
Exercises
Exams
Additional reactions of carboxylic acid derivatives are studied in this chapter: chemistry of acid anhydrides: preparation and reactions, chemistry of amides: preparation, hydrolysis and reactions, nomenclature and properties of nitriles, chemistry of nitriles: preparation, hydrolysis and reactions.
Preparation of Amides Reactions of Acid Anhydrides Hydrolysis and Reactions of Amides Nomenclature and Properties of Nitriles Hydrolysis and Reactions of Nitriles Preparation of Acid Anhydrides Preparation of Nitriles
The chemistry of the alpha carbon of a carbonyl is studied in this chapter: the alpha position, enols and tautomerization, the preparation of enolates and their reactivity, alpha halogenation, the haloform reaction, the alkylation of enolates, the malonic ester synthesis and acetoacetic ester synthesis.
Preparation of Enolates Enols and Tautomerization Enolate Alkylation Malonic Ester Synthesis The Alpha Position Enolate Reactivity Alpha Halogenation The Haloform Reaction Acetoacetic Ester Synthesis
Carbonyl condensation reactions are studied in this chapter: aldol and retro-aldol additions, aldol condensation, crossed aldol and intramolecular aldol reactions, Claisen condensation, Dieckmann cyclization, Michael reaction, Michael acceptors and donors, Stork enamine synthesis, Enamine Alkylation, Robinson annulation.
Aldol Reactions Crossed Aldol Reactions Robinson Annulation Claisen Condensations Michael Addition Enamine Alkylation Intramolecular Aldol Reactions The Dieckmann Cyclization Stork Enamine Synthesis
The benzylic and aromatic reactions of substituted benzene are studied in this chapter: reactivity of the benzylic position, benzylic oxidation and reduction, reduction of nitrobenzene, nucleophilic aromatic substitutions, elimination-addition via benzyne, reactivity of phenol, preparation and reactivity of diazonium salts.
Reactivity of the Benzylic Position Benzylic Oxidation and Reduction Reduction of Nitrobenzene Nucleophilic Aromatic Substitution Elimination-Addition via Benzyne Properties and Reactivity of Phenol Preparation of Diazonium Ions Substitution Reactions of Aryldiazonium Salts Coupling Reactions of Aryldiazonium Salts
Amines are studied in this chapter: nomenclature and properties of amines, preparation of amine by substitution reactions, reductive amination, and reductions, reactivity of amines, Hofmann elimination, reactions of amines with nitrous acid, Mannich reaction.
Nomenclature of Amines Properties of Amines Preparation of Amines via Substitution Reactions Preparation of Amines via Reductive Amination Reactivity of Amines Hofmann Elimination Reactions of Amines with Nitrous Acid Mannich Reaction
Heterocycles are studied in this chapter: reactivity of non-aromatic heterocycles, synthesis, properties and reactivity of aromatic heterocyclopentadienes, synthesis, properties and reactivity of pyridine
Nomenclature of Heterocycles Reactivity of Nonaromatic Heterocycles Aromatic Heterocyclopentadienes Aromatic Heterocyclopentadienes - Reactivity Pyridine Reactivity of Pyridine
Carbon-carbon bond formation is studied in this chapter: coupling reactions with organocuprate reagents, Suzuki reaction, Heck reaction, Sonogashira reaction, properties and preparation of carbenes, carbene reactivities, Simmons-Smith reaction, metathesis reaction.
Coupling Reactions with Organocuprate Reagents Suzuki Reaction Heck Reaction Sonogashira Reaction Properties and Preparation of Carbenes Reactivity of Carbenes Simmons-Smith Reaction Metathesis
Carbohydrates are studied in this chapter: properties of carbohydrates, Fischer projection, naming and classification of carbohydrates, configuration of aldoses and ketoses, cyclic structures of sugars, Haworth projection, ester, ether, and N-glycoside formation, epimerization, oxidation and reduction of sugars, chain lengthening and shortening, polysaccharides.
Naming and Classification of Carbohydrates Fischer Projection Cyclic Structures of Sugars Haworth Projections Reduction and Oxidation of Monosaccharides Reactions of Monosaccharides Polysaccharides Properties of Carbohydrates Configuration of Aldoses and Ketoses Chain Lengthening and Shortening
Amino acids, peptides, and proteins are studied in this chapter: structure and properties of amino acids, synthesis of amino acids (Hell-Volhard-Zelinsky reaction, amidomalonate synthesis, Strecker synthesis, enantiopure synthesis), structure and properties of peptides, peptide sequencing by Edman degradation and enzymatic cleavage, synthesis of peptides, Merrifield solid-phase peptide synthesis, structures and functions of proteins.
Structure and Properties of Amino Acids Synthesis of Amino Acids Structures of Peptides Peptide Sequencing Peptide Synthesis Automated Peptide Synthesis Synthesis of Enantiopure Amino Acids Protein Structure and Function
Lipids are studied in this chapter: classes of lipids, waxes, triglycerides, reactions of triglycerides and fatty acids, phospholipids, phosphoglycerides, steroid structure, cholesterol and other major steroids, biosynthesis of cholesterol, eicosanoids, prostaglandins, terpenes, classification and biosynthesis of terpenes.
Lipids Waxes Triglycerides and Fatty Acids Properties Reactions of Triglycerides Phospholipids Steroids Eicosanoids Terpenes
Midterm 1 includes 5 questions and it covers Organic Chemistry 1, Organic Chemistry 2 and Chapters 1, 2 and 3 of Organic Chemistry 3. At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 1.
Questions
60 Minutes
Midterm 2 includes 5 questions and it covers Organic Chemistry 1, Organic Chemistry 2 and chapters 1 to 6 of Organic Chemistry 3 (mainly chapters 4, 5 and 6). At the end of the test you can see the answers and determine whether you have solved the questions. You have 1 hour to resolve Midterm 2.
Questions
60 Minutes
Final Exam includes 13 questions and it covers all chapters of Organic Chemistry 1, 2 and 3. At the end of the test you can see the answers and determine whether you have solved the questions. You have 3 hours to resolve Final Exam.
Questions
180 Minutes