Quiz | Synthesis and Retrosynthesis Strategies
What is the good strategy in retrosynthetic analysis?
Work backwards (from the final product to immediate precursors …)
Count the number of carbons and determine the disconnections needed)
Check the available compounds and think about the immediate possible intermediate
All of the above
Which of the following conditions results in the formation of a C-C bond?
alkyl halide + EtONa
alcohol + CH3SOCl2
organometallics + alcohol
organometallics + carbonyls
How can you protect an alcohol?
(CH3)3COH in acid condition
(CH3)3COH in basic condition
Li to transform it into organometallic
PBr3 to transform it into alkyl halide
What kind of compounds should CH3MgBr react with to form propanol?
aldehyde
ketone
epoxide
alcohol
What is the first step of the formation of the butanone starting from methyl lithium and propanol?
oxidation of the propanol with Na2Cr2O7
oxidation of the propanol with PCC
protection of the alcohol
reduction of the alcohol with LiAlH4
What is the first step of the formation of the 1-methylcyclohexane-1,3-diol starting from methyllithium and 3-hydroxycyclohexanone?
oxidation of the alcohol with Na2Cr2O7
oxidation of the alcohol with PCC
protection of the alcohol
reduction of the ketone with LiAlH4
