Quiz | Electrophilic Attack on Derivatives of Benzene

1

Which of the following is not associated with electrophilic aromatic substitution?

The formation of nitrobenzene

The formation of benzene sulfonic acid

The formation of benzyne

The formation of bromobenzene

2

When considering electrophilic substitution reactions, the halides are described as:

ortho/para directing and activating

ortho/para directing and deactivating

meta directing and activating

meta directing and deactivating

3

When considering electrophilic substitution reactions, the methoxy substituent is described as:

ortho/para directing and activating

ortho/para directing and deactivating

meta directing and activating

meta directing and deactivating

4

When considering electrophilic substitution reactions, the nitro substituent is described as:

ortho/para directing and activating

ortho/para directing and deactivating

meta directing and activating

meta directing and deactivating

5

Which substituent is the strongest activator?

MeO

Br

NH2

NO2

6

What is the best synthetic strategy to alkylate bromobenzene in ortho position?

Friedel-Crafts Acylation followed by a reduction

Sulfonation, Friedel-Crafts Alkylation, Desulfonation

Substitution Nucleophile with halogenoalkane

Friedel-Crafts Alkylation followed by an elimination

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