Quiz | Carboxylic Acid Derivatives

1

What is the order of the carboxylic acid derivatives from the least reactive to the most reactive?

carboxylic anhydrides < esters < amides < acyl halides

esters < amides < acyl halides < carboxylic anhydrides

amides < esters < carboxylic anhydrides < acyl halides

acyl halides < carboxylic anhydrides < esters < amides

2

Which carboxylic acid derivatives has the most acidic proton on the α-carbon?

Ester

Amide

Carboxylic anhydride

Acyl halide

3

What is the typical chemical reaction of carboxylic acid derivatives?

Substitution nucleophile

Addition - Elimination

Reduction

Oxidation

4

Which of the following reagents transforms an ester into an aldehyde?

DIBAL-H

RMgBr

LiAlH4

NaOH / H2O

5

Which starting materials are required for a transesterification?

2 esters

Carboxylic acid + ester

Carboxylic acid + alcohol

Ester + alcohol

6

Which of the following reagents transforms an amide into an amine?

DIBAL-H

RMgBr

LiAlH4

H2SO4 / H2O

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