Quiz - Carbonyl Condensation Reactions - 1 | Carbonyl Condensation Reactions

Organic Chemistry 3 - Quiz - Carbonyl Condensation Reactions - 1

1

Which of the following compounds is the most acidic?

2

What is the first step of a Claisen condensation?

First step of a Claisen condensation: Deprotonation of the α position of an ester to form a nucleophilic ester enolate.

3

What is the product of an aldol condensation?

4

What is the product of the Claisen reaction between an ester and a ketone?

5

What are the different steps of a Robinson annulation?

Robinson annulation is a two-step ring-forming process in which Michael addition is followed by intramolecular aldol condensation.

6

In Stork enamine synthesis, what role does the carbonyl compound play?

The carbonyl compound reacts with the secondary amine to generate the enamine intermediate in Stork enamine synthesis.

7

Which of the following reagents is commonly used as a nucleophile in Michael addition reactions?

 

Enolate ions are commonly used as nucleophiles in Michael addition reactions due to their high nucleophilicity.

Michael addition:

8

Which of the following functional groups is commonly found in Michael acceptors?

 

Michael acceptors commonly contain an alkene functionality, which serves as the electrophilic center for nucleophilic addition reactions.

9

What is the main difference between the products of an aldol addition and an aldol condensation?

Aldol addition stops at the β-hydroxy aldehyde or ketone, while aldol condensation involves further dehydration to yield an α,β-unsaturated aldehyde or ketone, which involves forming a double bond by removing water.

10

Which of the following reagents reacts like β-Diesters during a Michael addition?