Quiz - Aldehydes and Ketones - 2 | Aldehydes and Ketones - Part 2
Organic Chemistry 2 - Quiz - Aldehydes and Ketones - 2
What is the expected product when a primary amine is added to an aldehyde under acidic conditions?
The reaction between a primary amine and an aldehyde under acidic conditions typically yields an imine. This involves the formation of a Schiff base through the nucleophilic addition of the amine to the carbonyl group followed by a dehydration step.
Which reagent is used in the Wolff-Kishner reduction to convert a carbonyl group to a methylene group?
The Wolff-Kishner reduction involves the conversion of a ketone or aldehyde to an alkane by treating it with hydrazine (NH2NH2) and then heating it with a strong base like potassium hydroxide. This results in the removal of the oxygen atom and the formation of a methylene group.
What is the outcome of the addition of cyanide ion to an aldehyde?
The addition of a cyanide ion (a nucleophile) to an aldehyde results in the formation of a cyanohydrin. The carbon of the cyanide ion attacks the electrophilic carbon of the carbonyl group, resulting in a carbon-carbon bond formation.
In the presence of a hydride donor like NaBH4, what is the expected reaction of an aldehyde?
A hydride donor such as sodium borohydride (NaBH4) is a reducing agent that transfers a hydride ion to the carbonyl carbon of an aldehyde, converting it to a primary alcohol through nucleophilic addition.
Which statement best describes the Wittig reaction between a phosphonium ylide and a ketone?
The Wittig reaction involves the reaction of a phosphonium ylide with a carbonyl compound like a ketone to form an alkene. The ylide acts as a nucleophile, attacking the electrophilic carbonyl carbon, and results in the formation of a carbon-carbon double bond.
During a Baeyer-Villiger oxidation, an aldehyde is converted into which functional group?
Baeyer-Villiger oxidation is a reaction where a carbonyl group, usually a ketone, is converted into an ester or a lactone. When an aldehyde is subjected to this reaction, it is converted into a carboxylic acid due to the insertion of an oxygen atom from a peroxide between the carbonyl carbon and its adjacent atom.
What product would you expect when a lithium carbanion derived from an alkyl lithium compound adds to an aldehyde?
The addition of a carbanion such as one derived from an alkyl lithium compound to an aldehyde results in the formation of an alkoxide intermediate, which upon protonation yields a secondary alcohol.
In a Wittig reaction, which functional group does the ylide initially form with the carbonyl carbon?
The initial product of the reaction between the ylide and the carbonyl carbon during the Wittig reaction is an oxaphosphetane, a four-membered ring intermediate. This intermediate eventually collapses to form an alkene and a triphenylphosphine oxide.
What is the initial intermediate formed during a Wolff-Kishner reduction?
The Wolff-Kishner reduction begins with the formation of a hydrazone by the reaction between the carbonyl compound and hydrazine. The hydrazone is then subjected to strong base, usually KOH or NaOH, leading to the elimination of nitrogen and formation of the methylene group.