Quiz - Carboxylic Acid Derivatives - 3 | Carboxylic Acid Derivatives – Part 2

Organic Chemistry 3 - Quiz - Carboxylic Acid Derivatives - 3

1

Which statement best describes the reactivity of acid anhydrides compared to esters?

Acid anhydrides are more reactive than esters due to the presence of two acyl groups which makes them more electrophilic. Therefore, nucleophiles attack them more readily than they do esters.

2

Which proton of an amide is the most acidic?

3

What is the first step in the Hofmann rearrangement?

The first step of the Hofmann rearrangement is an amidate formation

4

What are the products of the Hofmann rearrangement?

Hofmann Rearrangement:

5

Which of the following statements is incorrect about alkanenitriles?

Nitriles take precedence over aldehydes, ketones, amines, alkenes, alkynes but not over carboxylic acids

6

Which of the following reagents converts a nitrile to an aldehyde?

Reduction of nitriles resulting in the formation of aldehydes:

7

What is the product of the hydrolysis of nitriles?

Hydrolysis of nitriles:

8

What is the IUPAC name of CN-CH2CH2-COOH?

The IUPAC name for CN-CH₂CH₂-COOH is "3-Cyanopropanoic acid," indicating the presence of a cyano group attached to the third carbon of the propanoic acid structure.

9

Among carboxylic acid derivatives, which one typically exhibits the highest reactivity in nucleophilic acyl substitution reactions?

Anhydrides generally exhibit higher reactivity in nucleophilic acyl substitution reactions compared to other carboxylic acid derivatives due to the presence of two electrophilic acyl groups in the molecule.

10

What is the primary product obtained when nitriles react with organometallic reagents in nucleophilic addition reactions?

The reaction of nitriles with organometallic reagents typically results in the formation of ketones through nucleophilic addition to the nitrile carbon.