Quiz - Carboxylic Acid Derivatives | Carboxylic Acid Derivatives

1

Which proton of an amide is the most acidic?

The proton on the carbonyl

The proton on the nitrogen atom

The proton on the carbon atom in α position

It depends on the conditions (temperature and concentration)

2

What is the first step in the Hofmann rearrangement?

Nucleophilic attack of the hydroxide ion on the carbonyl

Acid-activation of the carbonyl

Halogenation of the amide

Deprotonation of the amide and formation of an amidate

Step 1 in the Hofmann rearrangement: amidate formation

Concepts related to this Question

Hofmann Rearrangement

3

What are the products of the Hofmann rearrangement?

An amine and CO₂

An amide and CO₂

An amine and NH₃

A carboxylic acid and NH₃

Hofmann Rearrangement:

Concepts related to this Question

Hofmann Rearrangement

4

Which of the following statements is incorrect about alkanenitriles?

The substituent -CN is called cyano

CN is linear and carbon and nitrogen atoms are sp-hybridized

Nitriles take precedence over carboxylic acids in the nomenclature

A cycloalkane with a nitrile substituent is called cycloalkanecarbonitrile

Nitriles take precedence over aldehydes, ketones, amines, alkenes, alkynes but not over carboxylic acids

Concepts related to this Question

Alkanenitriles: Nomenclature and Properties

5

Which of the following reagents converts a nitrile to an aldehyde?

LiAlH₄

R₂AlH

H₂, PtO₂

RMgBr

Reduction of nitriles resulting in the formation of aldehydes:

Concepts related to this Question

Reduction of Nitriles

6

What is the product of the hydrolysis of nitriles?

An alcohol

An aldehyde

A ketone

A carboxylic acid

Hydrolysis of nitriles:

Concepts related to this Question

Hydrolysis of Nitriles

Quiz - Carboxylic Acid Derivatives | Carboxylic Acid Derivatives – Part 2

Organic Chemistry 3 - Quiz - Carboxylic Acid Derivatives