Quiz | Carboxylic Acid Derivatives – Part 2
Which proton of an amide is the most acidic?
The proton on the carbonyl
The proton on the nitrogen atom
The proton on the carbon atom in α position
It depends on the conditions (temperature and concentration)
What is the first step of the Hofmann rearrangement?
Nucleophile attack of the hydroxide ion on the carbonyl
Acid-activation of the carbonyl
Halogenation of the amide
Deprotonation of the amide and formation of an amidate
What are the products of the Hofmann rearrangement?
An amine and CO2
An amide and CO2
An amine and NH3
A carboxylic acid and NH3
Which statement is incorrect about alkanenitriles?
The substituent -CN is called cyano
CN is linear and the carbon and the nitrogen atoms are sp-hybridized
Nitrile takes precedence over carboxylic acid in naming
A cycloalkane with a nitrile substituent is called cycloalkanecarbonitriles
Which of the following reagents transforms a nitrile into an aldehyde?
LiAlH4
R2AlH
H2, PtO2
RMgBr
What is the product of the hydrolysis of nitriles?
An alcohol
An aldehyde
A ketone
A carboxylic acid
