Quiz - Benzylic and Aromatic Reactions - 3 | Benzylic and Aromatic Reactions of Substituted Benzene

Organic Chemistry 3 - Quiz - Benzylic and Aromatic Reactions - 3


Which reaction condition is typically used for the benzylic oxidation of toluene to benzoic acid?

Benzylic oxidation of toluene to benzoic acid is commonly carried out using potassium permanganate (KMnO4) in water. This oxidative process targets the relatively electron-rich benzylic position, transforming a methyl group into a carboxylic acid functionality.


Which reagent combination is typically used in Clemmensen reduction for converting an aryl ketone to an alkylbenzene?

Clemmensen reduction involves the use of zinc and mercury in the presence of a strong acid to convert an aryl ketone to an alkylbenzene.


What role does hydrazine (NH2NH2) play in Wolff-Kishner reduction?

In Wolff-Kishner reduction, hydrazine (NH2NH2) serves as the reducing agent, facilitating the conversion of an aryl ketone to an alkylbenzene.


What type of substituent is most conducive to azo coupling reactions?

Activated rings with electron-donating groups, such as phenol or aminobenzene, work best as nucleophiles in azo coupling reactions.


What is the primary purpose of substitution reactions involving aryldiazonium salts?

Substitution reactions of aryldiazonium salts serve as a straightforward method for introducing a variety of functional groups onto aromatic rings.


In radical bromination at the benzylic position, what initiates the formation of a benzylic radical?

The homolytic cleavage of a bromine-bromine bond initiates the formation of a bromine radical, which subsequently abstracts a hydrogen atom from the benzylic position, leading to the formation of a benzylic radical.


What is a Meisenheimer complex in the context of nucleophilic aromatic substitution (SNAr) reactions?

The Meisenheimer complex is a stabilized, negatively charged intermediate formed during nucleophilic aromatic substitution reactions, where the negative charge is resonance stabilized throughout the ring.


Which functional group is typically required on the aromatic ring for a successful SNAr reaction?

SNAr reactions typically require a strong electron-withdrawing group on the aromatic ring, with the nitro group being a common choice.


What is the primary intermediate formed in the elimination-addition process with bromobenzene?

The elimination-addition reaction via benzyne mechanism involves the formation of a benzyne intermediate, which is a highly reactive triple-bonded carbon species.


What form of phenol is favored due to its aromatic nature?

The enol form of phenol, favored by its aromaticity, contributes to its unique reactivity and acidity.