Quiz - Amines - 2 | Amines
Organic Chemistry 3 - Quiz - Amines - 2
Which of the following is the correct IUPAC name for tert-butylamine?
The correct IUPAC name for tertiary-butylamine is 2-methylpropan-2-amine. This nomenclature follows the rules of identifying the longest carbon chain attached to the nitrogen (propane), the location of the substituent (2-methyl), and the amine group at the end of the name.
Which characteristic feature of amines affects their boiling points?
Amines can form hydrogen bonds due to the lone pair on the nitrogen, which significantly affects their boiling points. Higher ability to form hydrogen bonds correlates with higher boiling points.
What is the main product of the reaction between an amine and a haloalkane in a substitution reaction?
In a substitution reaction between an amine and a haloalkane, the amine acts as a nucleophile and replaces the halide ion, forming an alkylamine as the main product.
What is the significance of reductive amination in the synthesis of amines?
Reductive amination is key in amine synthesis as it involves the conversion of aldehydes or ketones into amines by reacting with ammonia or an amine and reducing the intermediate imine.
During Hofmann elimination, which of the following is eliminated to form an alkene?
In Hofmann elimination, an amine is first converted to an ammonium salt with methyl iodide, which is then eliminated as a tertiary amine to form an alkene. The elimination involves the least substituted hydrogen atom to give the most stable product.
What is the expected outcome when a primary amine reacts with nitrous acid (HNO2)?
When a primary amine reacts with nitrous acid, it forms a diazonium salt. This reaction is commonly used in diazotization processes.
In the Mannich reaction, a primary or secondary amine reacts with formaldehyde and a compound with an active hydrogen atom. What type of compound is typically formed?
The Mannich reaction typically yields a beta-amino carbonyl compound, which demonstrates connectivity between amines, carbonyl chemistry, and carbon-carbon bond formation.
Which factor determines the reactivity of amines towards electrophiles?
The basicity of amines determines their reactivity towards electrophiles. More basic amines have a higher electron density on nitrogen, making them more nucleophilic and thus more reactive towards electrophiles.
What is the expected major product when an amine undergoes acylation with an acid chloride?
Acylation of an amine with an acid chloride typically yields an amide. The acyl group from the acid chloride replaces one of the amine's hydrogens.
Why are aryldiazonium ions relatively stable compared to alkyldiazonium ions?
Aryldiazonium ions are stabilized by resonance, which disperses the positive charge over the aromatic ring, making them relatively stable and suitable for use as synthetic intermediates.