Quiz - Amines - 1 | Amines
Organic Chemistry 3 - Quiz - Amines - 1
Which of the following molecules is a secondary amine?
Which of the following statements is correct about ethylamine?
Amines have properties similar to alcohols and ethers. They can serve as nucleophile and participate in hydrogen bonding (high boiling point + soluble in water). However, oxygen is more electronegative than nitrogen ⇒ amines have weaker hydrogen bonding than alcohols and so lower boiling point.
Which of the following statement about the reaction between 1-bromopropane and ammonia is incorrect?
Which of the following statements about the reaction between pentanenitrile and LiAlH4 is correct?
Which of the following reagents is used for the reductive amination of an aldehyde?
Amines by reductive amination - Reduction step:
What is the chemical function of the major product of a Hofmann elimination?
Hofmann elimination:
Why are alkyldiazonium salts too reactive to be isolated?
Alkyldiazonium salts are too reactive to be isolated because they can spontaneously release nitrogen gas to form highly reactive carbocations, leading to a mixture of substitution, elimination, and rearrangement products.
What is the key advantage of the Gabriel synthesis for the preparation of amines?
The Gabriel synthesis method avoids overalkylation, allowing for the selective synthesis of primary amines without the formation of secondary or tertiary amines.
What is the first step in the mechanism of the Mannich reaction?
The first step in the Mannich reaction mechanism involves the nucleophilic addition of the amine to the carbonyl group of the aldehyde or ketone, resulting in the formation of an iminium ion. This step initiates the formation of the β-aminoalkyl carbonyl compound.
Why are amines containing 3 different alkyl groups not optically active at room temperature?
Amines with three different alkyl groups possess a chiral center at the nitrogen atom. However, they rapidly undergo pyramidal inversion, interconverting between enantiomeric forms. As a result, they do not exhibit optical activity at room temperature.